Direct Synthetic Approach to N– Aminoimidazole–2–thiones and Imidazole Derivatives

Three Component Syntheses of Pyrrolo Imidazole Derivatives in the Presence of N-methyl imidazole, Activated Acetylenes and Phenylsulfonylacetophenone

Because of the significant role in biological processes in living cells and the diverse types of physiological activities, heterocyclic compounds are in focus of intense investigations by academic, industry and applied-oriented chemists. Considerably, ascientific renaissance of heterocycles during the last decades is closely related to the development of multicomponent approaches to their s...

Reversal by Imidazole Derivatives

cus aureus by heat shock. The effect has then been more thoroughly investigated by landolo and Ordal (5, 6). Since heat shock causes an increased sensitivity of fungal cells to high temperature and blue light (2-4), it seemed justified also to test the response of heat-shocked fungal cells to high concentrations of sodium chloride. Most experiments were performed with the ascomycete Ophiostoma ...

three component syntheses of pyrrolo imidazole derivatives in the presence of n-methyl imidazole, activated acetylenes and phenylsulfonylacetophenone

Design and Synthesis of New Imidazole Derivatives of Captopril

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.

Design and Synthesis of New Imidazole Derivatives of Captopril

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.